Articles
Clinical
- Osu N, Musha A, Yumisaki H, Okada K, Kubo N, Okano N, Takayasu Y, Shino M, Nikkuni O, Ida S, Kawamura H, Chikamatsu K, Ohno T. The Efficacy of Radiotherapy without Surgery for External Auditory Canal Squamous Cell Carcinoma. J Clin Med. 2022 Oct 6;11(19):5905. doi: 10.3390/jcm11195905. PMID: 36233771; PMCID: PMC9571158.
- Musha A, Kubo N, Kawamura H, Okano N, Sato H, Okada K, Osu N, Yumisaki H, Adachi A, Takayasu Y, Shino M, Nikkuni O, Ida S, Shirai K, Saitoh JI, Yokoo S, Chikamatsu K, Ohno T. Carbon-ion Radiotherapy for Inoperable Head and Neck Bone and Soft-tissue Sarcoma: Prospective Observational Study. Anticancer Res. 2022 Mar;42(3):1439-1446. doi: 10.21873/anticanres.15614. PMID: 35220237.
- Musha A, Hirai C, Kitada Y, Tsunoda A, Shimada H, Kubo N, Kawamura H, Okano N, Sato H, Okada K, Adachi A, Yokoo S, Chikamatsu K, Ohno T. Relationship between oral mucositis and the oral bacterial count in patients with head and neck cancer undergoing carbon ion radiotherapy: A prospective study. Radiother Oncol. 2022 Feb;167:65-71. doi: 10.1016/j.radonc.2021.12.010. Epub 2021 Dec 10. PMID: 34902372.
- Ohtaka T, Shiba S, Shibuya K, Okazaki S, Miyasaka Y, Tomizawa K, Okamoto M, Ohno T. Long-term survivor of hepatocellular carcinoma treated with repeated carbon ion radiotherapy and transarterial chemoembolization: a case report Clin J Gastroenterol. 2022 Aug;15(4):771-775. doi: 10.1007/s12328-022-01642-4. Epub 2022 Jun 9.
- Darwis NDM, Horigome E, Li S, Adachi A, Oike T, Shibata A, Hirota Y, Ohno T. Radiosensitization by the Selective Pan-FGFR Inhibitor LY2874455 Cells. 2022 May 24;11(11):1727. doi: 10.3390/cells11111727.
- Adachi A, Oike T, Tamura M, Ota N, Ohno T. Radiotherapy With Hydrogen Peroxide-Soaked Gauze for Preauricular Sebaceous Carcinoma Cureus. 2022 Jul 29;14(7):e27464. doi: 10.7759/cureus.27464. eCollection 2022 Jul.
- Okano N, Yumisaki H, Saito S, Kubo N, Okada K, Kawamura H, Yasuda M, Ohno T. Definitive Radiotherapy Using Electron Beam and Intensity-modulated Radiotherapy for Unresectable Angiosarcoma of the Scalp Anticancer Res. 2022 Dec;42(12):5991-5997. doi: 10.21873/anticanres.16110.
- Kubo N, Okano N, Kawamura H, Uchiyama A, Ohno T. Radiotherapy for Epstein-Barr Virus-Positive Mucocutaneous Ulcer at the Lower Leg Skin: A Case Report Cureus. 2022 Oct 31;14(10):e30936. doi: 10.7759/cureus.30936. eCollection 2022 Oct.
- Murakami N, Ohno T, Toita T, Ando K, Ii N, Okamoto H, Kojima T, Tsujino K, Masui K, Yoshida K, Ikushima H. Japanese Society for Radiation Oncology Consensus Guidelines of combined intracavitary and interstitial brachytherapy for gynecological cancers J Radiat Res. 2022 May 18;63(3):402-411. doi: 10.1093/jrr/rrac011.
- Takahashi D, Demizu Y, Koto M, Kubo N, Suefuji H, Ikawa H, Ohno T, Shioyama Y, Okimoto T, Tsuji H; Japan Carbon-Ion Radiation Oncology Study Group. Multicenter study of re-irradiation using carbon-ions for head and neck malignancies after photon radiotherapy Cancer Med. 2022 Oct;11(19):3593-3601. doi: 10.1002/cam4.4741. Epub 2022 Apr 7.
- Murakami N, Ando K, Murata M, Murata K, Ohno T, Aoshika T, Kato S, Okonogi N, Saito AI, Kim JY, Yoshioka Y, Sekii S, Tsujino K, Lowanichkiattikul C, Pattaranutaporn P, Kaneyasu Y, Nakagawa T, Watanabe M, Uno T, Umezawa R, Jingu K, Kanemoto A, Wakatsuki M, Shirai K, Igaki H, Itami J. An Asian multi-national multi-institutional retrospective study comparing intracavitary versus the hybrid of intracavitary and interstitial brachytherapy for locally advanced uterine cervical carcinoma J Radiat Res. 2022 May 18;63(3):412-427. doi: 10.1093/jrr/rrac014.
- Murakami N, Watanabe M, Uno T, Sekii S, Tsujino K, Kasamatsu T, Machitori Y, Aoshika T, Kato S, Hirowatari H, Kaneyasu Y, Nakagawa T, Ikushima H, Ando K, Murata M, Yoshida K, Yoshioka H, Murata K, Ohno T, Okonogi N, Saito A, Ichikawa M, Okuda T, Tsuchida K, Sakurai H, Yoshimura R, Yoshioka Y, Yorozu A, Okamoto H, Inaba K, Kato T, Igaki H, Itami J. Large volume was associated with increased risk of acute non-hematologic adverse events in the hybrid of intracavitary and interstitial brachytherapy for locally advanced uterine cervical cancer: preliminary results of prospective phase I/II clinical trial Jpn J Clin Oncol. 2022 Aug 5;52(8):859-868. doi: 10.1093/jjco/hyac072.
- Sakai M, Sohda M, Uchida S, Yamaguchi A, Watanabe T, Saito H, Ubukata Y, Nakazawa N, Kuriyama K, Sano A, Ogawa H, Yokobori T, Noda SE, Ohno T, Shirabe K, Saeki H. Concurrent Chemoradiotherapy With Docetaxel, Cisplatin, and 5-Fluorouracil (DCF-RT) for Patients With Potentially Resectable Esophageal Cancer Anticancer Res. 2022 Oct;42(10):4929-4935. doi: 10.21873/anticanres.15999.
- Kanbe M, Sunaga N, Hara K, Sawada H, Wakamatsu I, Hara K, Muto S, Sawada Y, Masubuchi H, Sato M, Miura Y, Tsurumaki H, Yatomi M, Sakurai R, Koga Y, Ohtaki Y, Nagashima T, Okano N, Kubo N, Maeno T, Hisada T. Durable response to afatinib rechallenge in a long-term survivor of non-small cell lung cancer harboring EGFR L858R and L747V mutations Thorac Cancer. 2022 Nov;13(22):3225-3228. doi: 10.1111/1759-7714.14678. Epub 2022 Oct 4.
- Murakami N, Watanabe M, Uno T, Sekii S, Tsujino K, Kasamatsu T, Machitori Y, Aoshika T, Kato S, Hirowatari H, Kaneyasu Y, Nakagawa T, Ikushima H, Ando K, Murata M, Yoshida K, Yoshioka H, Murata K, Ohno T, Okonogi N, Saito AI, Ichikawa M, Okuda T, Tsuchida K, Sakurai H, Yoshimura R, Yoshioka Y, Yorozu A, Kunitake N, Okamoto H, Inaba K, Kato T, Igaki H, Itami J. Phase I/II prospective clinical trial for the hybrid of intracavitary and interstitial brachytherapy for locally advanced uterine cervical cancer J Gynecol Oncol. 2023 May;34(3):e24. doi: 10.3802/jgo.2023.34.e24. Epub 2022 Dec 21.
- Sunaga N, Miura Y, Sakurai R, Ohshima S, Uno S, Muto S, Sato M, Tsurumaki H, Yatomi M, Koga Y, Ohtaki Y, Nagashima T, Okano N, Kubo N, Maeno T, Hisada T. Sustained antitumor response to lenvatinib with weekend-off and alternate-day administration in chemotherapy-refractory thymic carcinoma: a case report Anticancer Drugs. 2023 Apr 1;34(4):605-608. doi: 10.1097/CAD.0000000000001474. Epub 2022 Dec 5.
- Musha A, Hirai C, Kitada Y, Tsunoda A, Shimada H, Kubo N, Kawamura H, Okano N, Sato H, Okada K, Adachi A, Yokoo S, Chikamatsu K, Ohno T. Relationship between oral mucositis and the oral bacterial count in patients with head and neck cancer undergoing carbon ion radiotherapy: A prospective study. Radiother Oncol. 2021 Dec 10:S0167-8140(21)09054-X. doi: 10.1016/j.radonc.2021.12.010. Epub ahead of print. PMID: 34902372.
- Musha A, Kubo N, Okano N, Kaminuma T, Kawamura H, Sato H, Takayasu Y, Shino M, Nikkuni O, Ida S, Shirai K, Saitoh JI, Ogawa M, Yokoo S, Chikamatsu K, Ohno T, Working Group on Head and Neck Tumors. Prospective observational study of carbon-ion radiotherapy for non-squamous cell carcinoma of the head and neck in Gunma University. Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology. 2021 inpress doi: 10.1016/j.ajoms.2021.10.012
- Kubo N, Sakai M, Kawamura H, Oike T, Kubota Y, Anakura M, Adachi A, Sato H, Musha A, Okano N, Kaminuma T, Shirai K, Saitoh JI, Yokoo S, Chikamatsu K, Ohno T. Dosimetric Parameters Predicting Tooth Loss after Carbon Ion Radiotherapy for Head and Neck Tumors. Radiation. 2021; 1(3):183-193. doi: 10.3390/radiation1030017
- Musha A, Kubo N, Okano N, Kawamura H, Miyasaka Y, Sato H, Takayasu Y, Chikamatsu K, Yokoo S, Ohno T. Oral findings during follow-up of nasopharyngeal squamous cell carcinoma treatment: A case report. SAGE Open Med Case Rep. 2021 Jul 20;9:2050313X211033037. doi: 10.1177/2050313X211033037. PMID: 34367642; PMCID: PMC8299874.
- Musha A, Shimada H, Kubo N, Kawamura H, Okano N, Sato H, Kaminuma T, Okada K, Anakura M, Adachi A, Shirai K, Saitoh JI, Yokoo S, Chikamatsu K, Ohno T. Clinical features and dosimetric evaluation of carbon ion radiation-induced osteoradionecrosis of mandible in head and neck tumors. Radiother Oncol. 2021 Aug;161:205-210. doi: 10.1016/j.radonc.2021.06.022. Epub 2021 Jun 18. PMID: 34147522.
- Musha A, Ohno T. Subcutaneous Emphysema Caused by Third Molar Extraction. OTO Open. 2021 Mar 29;5(1):2473974X211004527. doi: 10.1177/2473974X211004527. PMID: 33855255; PMCID: PMC8010816.
- Kobayashi D, Abe T, Saitoh JI, Oike T, Sato H, Musha A, Mizukami T, Shimizu T, Nakano T, Ohno T. Stereotactic body radiotherapy for adenoid cystic carcinoma metastatic to the lung: a case report. J Med Case Rep. 2021 Apr 11;15(1):156. doi: 10.1186/s13256-021-02781-x. PMID: 33838695.
- Okano N, Sakai M, Shibuya K, Tsuda K, Kanzaki T, Sano M, Kaneko Y, Ohno T. Safety verification of carbon-ion radiotherapy for patients with cardiac implantable electronic devices (CIEDs) Journal of Radiation Research 2022; 63 1 122 doi:10.1093/jrr/rrab105
- Shiba S, Sakai M, Okamoto M, Ohno T. Visualisation of Range Shortening in Carbon Ion Beams and Washout of Positron Emitter: First-in-Human Report. In Vivo 2021; 35 6 3521 doi:10.21873/invivo.12654
- Shiba S, Okamoto M, Tashiro M, Ogawa H, Osone K, Yanagawa T, Kohama I, Okazaki S, Miyasaka Y, Osu N, Chikuda H, Saeki H, Ohno T. Rectal dose-sparing effect with bioabsorbable spacer placement in carbon ion radiotherapy for sacral chordoma: dosimetric comparison of a simulation study. J Radiat Res. 2021;62(3):549-555. doi: 10.1093/jrr/rrab013.
- 武者 篤.放射線性口腔粘膜炎の発症予測(北関東医学会奨励賞) The Kitakanto Medical Journal. 2021 71(1):77-78. doi : 10.2974/kmj.71.77
- 武者 篤,久保亘輝,岡野奈緒子,神沼拓也,河村英将,佐藤浩央,高安幸弘,紫野正人,新國 摂,井田翔太,白井克幸,齋藤淳一,小川 将,横尾 聡,近松一朗,大野達也. 群馬大学における頭頸部非扁平上皮癌に対する重粒子線治療. 頭頸部癌 2021 47(1):53-58.
- 大須直人, 尾池貴洋. 放射線治療におけるprecision medicine戦略. Precision Medicine 2021;4:1–4.
- Shirai K, Suzuki M, Akahane K, Takahashi Y, Kawahara M, Yamada E, Wakatsuki M, Ogawa K, Takahashi S, Minato K, Hamamoto K, Saito K, Oshima M, Konishi T, Nakamura Y, Washino S, Miyagawa T. Dose-volume Histogram-based Predictors for Hematuria and Rectal Hemorrhage in Patients Receiving Radiotherapy After Radical Prostatectomy. In Vivo 2020;34(3):1289-1295.
- Abe T, Kobayashi N, Aoshika T, Ryuno Y, Saito S, Igari M, Hirai R, Kumazaki YU, Miura YU, Kaira K, Kagamu H, Noda SE, Kato S. Pattern of Local Failure and its Risk Factors of Locally Advanced Non-small Cell Lung Cancer Treated With Concurrent Chemoradiotherapy. Anticancer Res 2020;40(6):3513-3517.
- Faisal HH, Kubo N, Nuryadi E, Prihartono J, Atmakusuma TD, Rachmadi L, Oike T, Nakano T, Gondhowiardjo SA, Adham M. Patterns of Care and Outcome Analysis of Nasopharyngeal Carcinoma: An Indonesian Single Institution Study. Asian Pac J Cancer Prev 2020;21(5):1481-1485.
- Takakusagi Y, Katoh H, Kano K, Anno W, Tsuchida K, Mizoguchi N, Serizawa I, Yoshida D, Kamada T. Preliminary result of carbon-ion radiotherapy using the spot scanning method for prostate cancer. Radiat Oncol 2020;15(1):127.
- Okonogi N, Wakatsuki M, Mizuno H, Fukuda S, Cao J, Kodrat H, Lau FN, Calaguas MJ, de Los Reyes RH, Chansilpa Y, Uddin AFMK, Adylkhanov T, Cho CK, Tsegmed U, Hoang NC, Ohno T, Nakano T, Kato S; Forum for Nuclear Cooperation in Asia. Preliminary survey of 3D image-guided brachytherapy for cervical cancer at representative hospitals in Asian countries. J Radiat Res 2020;61(4):608-615.
- Sato H, Okonogi N, Nakano T. Rationale of combination of anti-PD-1/PD-L1 antibody therapy and radiotherapy for cancer treatment. Int J Clin Oncol 2020;25(5):801-809.
- Adachi A, Kawamura H, Yoshida D, Kawahara M, Kudo S, Ebara T, Nakano T. Wholebladder Radiation Therapy for Lymph Node-negative Bladder Cancer With Muscle Invasion in Elderly Patients. Anticancer Res 2020;40(5):2905-2909.
- Irie D, Murata K, Kaminuma T, Oike T, Ohno T. Oral Gastrografin Facilitates Delineation of Intestinal Tracts in CT-Based Brachytherapy for Uterine Cervical Cancer. Cureus 2020;12(5):e8367.
- Tomizawa K, Kaminuma T, Murata K, Noda SE, Irie D, Kumazawa T, Oike T, Ohno T. FIGO 2018 Staging for Cervical Cancer: Influence on Stage Distribution and Outcomes in the 3D-Image-Guided Brachytherapy Era. Cancers (Basel) 2020;12(7):1770.
- Tomizawa K, Miyazaki T, Yamaguchi A, Honda R, Hoshino M, Yanai M, Miyamae Y, Kurosaki R, Shimizu H, Arakawa K, Ide M. Malignant peripheral nerve sheath tumour of the oesophagus: a case report. Surg Case Rep 2020;6(1):186.
- Tsuchida K, Inaba K, Kashihara T, Murakami N, Okuma K, Takahashi K, Igaki H, Nakayama Y, Maejima A, Shinoda Y, Matsui Y, Komiyama M, Fujimoto H, Ito Y, Sumi M, Nakano T, Itami J. Clinical outcomes of definitive whole pelvic radiotherapy for clinical lymph node metastatic prostate cancer. Cancer Med 2020;9(18):6629-6637.
- Darwis NDM, Oike T, Kubo N, Gondhowiardjo SA, Ohno T. Characteristics of PSA Bounce after Radiotherapy for Prostate Cancer: A Meta-Analysis. Cancers (Basel) 2020;12(8):2180.
- Shiba S, Shibuya K, Okamoto M, Okazaki S, Komatsu S, Kubota Y, Nakano T, Ohno T. Clinical impact of Hypofractionated carbon ion radiotherapy on locally advanced hepatocellular carcinoma. Radiat Oncol 2020;15(1):195.
- Kobayashi N, Abe T, Noda SE, Kumazaki YU, Hirai R, Igari M, Aoshika T, Saito S, Ryuno Y, Kato S. Stereotactic Body Radiotherapy for Pulmonary Oligometastasis from Colorectal Cancer. In Vivo 2020;34(5):2991-2996.
- Abe T, Ryuno Y, Saito S, Aoshika T, Igari M, Hirai R, Kumazaki Y, Kaira K, Kagamu H, Ishida H, Noda SE, Kato S. Stereotactic body radiation therapy using CyberKnife for T1N0M0 lung cancer patients with severe pulmonary dysfunction. J Radiat Res 2020;61(6):903-907.
- Okonogi N, Shinnosuke M, Fukahori M, Furuichi W, Inaniwa T, Matsufuji N, Imai R, Yamada S, Kanematsu N, Tsuji H. Dose-averaged linear energy transfer per se does not correlate with late rectal complications in carbon-ion radiotherapy. Radiother Oncol 2020;153:272-278.
- Kubo N, Kubota Y, Oike T, Kawamura H, Sakai M, Imamura A, Komatsu S, Miyasaka Y, Sato H, Musha A, Okano N, Shirai K, Saitoh JI, Chikamatsu K, Ohno T. Skin Dose Reduction by Layer-Stacking Irradiation in Carbon Ion Radiotherapy for Parotid Tumors. Front Oncol 2020;10:1396.
- Musha A, Shimada H, Kubo N, Kawamura H, Okano N, Miyasaka Y, Sato H, Shirai K, Saitoh JI, Yokoo S, Chikamatsu K, Ohno T. Evaluation of Carbon Ion Radiation-Induced Trismus in Head and Neck Tumors Using Dose-Volume Histograms. Cancers 2020;12(11):3116.
- Takakusagi Y, Oike T, Kano K, Anno W, Tsuchida K, Mizoguchi N, Serizawa I, Yoshida D, Katoh H, Kamada T. Prostate-specific antigen dynamics after neoadjuvant androgen-deprivation therapy and carbon ion radiotherapy for prostate cancer. PLoS One 2020;15(11):e0241636.
- Yoshimoto Y, Sasaki Y, Murata K, Noda SE, Miyasaka Y, Hamamoto J, Furuya M, Hirato J, Suzuki Y, Ohno T, Tokino T, Oike T, Nakano T. Mutation profiling of uterine cervical cancer patients treated with definitive radiotherapy. Gynecol Oncol 2020;159(2):546-553.
- Abe T, Saito S, Iino M, Aoshika T, Ryuno Y, Ohta T, Igari M, Hirai R, Kumazaki Y, Ebihara Y, Nakahira M, Sugasawa M, Noda SE, Kato S. Results of definitive radiotherapy with concurrent chemotherapy for maxillary sinus carcinomas with neck lymph node metastasis. J Radiat Res 2021;62(1):104-109.
- Abe T, Saito S, Iino M, Aoshika T, Ryuno Y, Ohta T, Igari M, Hirai R, Kumazaki Y, Miura Y, Kaira K, Kagamu H, Noda SE, Kato S. Effect of durvalumab on local control after concurrent chemoradiotherapy for locally advanced non-small cell lung cancer in comparison with chemoradiotherapy alone. Thorac Cancer 2021;12(2):245-250.
- Takakusagi Y, Yoshida D, Kusano Y, Kano K, Anno W, Tsuchida K, Mizoguchi N, Serizawa I, Katoh H, Imura K, Takayama Y, Minohara S, Kamada T. Dosimetric Comparison Between Carbon-ion Radiotherapy and Photon Radiotherapy for Stage I Esophageal Cancer. In Vivo 2021;35(1):447-452.
- Miyasaka Y, Komatsu S, Abe T, Kubo N, Okano N, Shibuya K, Shirai K, Kawamura H, Saitoh JI, Ebara T, Ohno T. Comparison of Oncologic Outcomes between Carbon Ion Radiotherapy and Stereotactic Body Radiotherapy for Early-Stage Non-Small Cell Lung Cancer. Cancers (Basel) 2021;13(2):176.
- Puspitasari A, Cerri M, Takahashi A, Yoshida Y, Hanamura K, Tinganelli W. Hibernation as a Tool for Radiation Protection in Space Exploration. Life (Basel) 2021;11(1):54.
- Otani Y, Ohno T, Ando K, Murata K, Kato S, Noda SE, Murofushi K, Ushijima H, Yoshida D, Okonogi N, Isohashi F, Wakatsuki M, Nakano T. Dosimetric feasibility of computed tomography-based image-guided brachytherapy in locally advanced cervical cancer: a Japanese prospective multi-institutional study. J Radiat Res 2021;rraa138.
- Sato H, Demaria S, Ohno T. The role of radiotherapy in the age of immunotherapy. Jpn J Clin Oncol 2021;51(4):513-522.
- Okamoto M, Shiba S, Okazaki S, Miyasaka Y, Shibuya K, Kiyohara H, Ohno T. Feasibility and Safety of Repeated Carbon Ion Radiotherapy for Locally Advanced Unresectable Pancreatic Cancer. Cancers (Basel) 2021;13(4):665.
- Musha A, Ohno T. Subcutaneous Emphysema Caused by Third Molar Extraction. OTO Open. 2021 5(1):1-2
- 武者 篤.放射線性口腔粘膜炎の発症予測. The Kitakanto Medical Journal. 2021 71(1):77-78.
- Musha A, Fukata K, Saitoh JI, Shirai K, Abe T, Mizukami T, Kawashima M, Yokoo S, Chikamatsu K, Ohno T, Nakano T. Tongue surface model can predict radiation tongue mucositis due to intensity-modulated radiation therapy for head and neck cancer. Int J Oral Maxillofac Surg. 2020 Jan;49(1):44-50.
- Ohno T, Okamoto M. Carbon ion radiotherapy as a treatment modality for paediatric cancers. Lancet Child Adolesc Health. 2019;3(6):371-372.
- Okonogi N, Kaminuma T, Okimoto T, Shinoto M, Yamamoto N, Yamada S, Murata K, Ohno T, Shioyama Y, Tsuji H, Nakano T, Kamada T. Carbon-ion radiotherapy for lymph node oligo-recurrence: a multi-institutional study by the Japan Carbon-Ion Radiation Oncology Study Group (J-CROS). Int J Clin Oncol. 2019;24(9):1143-1150.
- Shirai K, Ohno T, Saitoh JI, Okamoto M, Katoh H, Murata K, Kawamura H, Musha A, Abe T, Mizukami T, Akahane K, Nakano T. Prospective Study of Isolated Recurrent Tumor Re-irradiation With Carbon-Ion Beams. Front Oncol. 2019;9:181.
- Murata H, Okonogi N, Wakatsuki M, Kato S, Kiyohara H, Karasawa K, Ohno T, Nakano T, Kamada T, Shozu M, The Working Group Of Gynecological Tumors TWGOG. Long-Term Outcomes of Carbon-Ion Radiotherapy for Malignant Gynecological Melanoma. Cancers (Basel). 2019;11(4).
- Okazaki S, Murata K, Noda SE, Kumazaki Y, Hirai R, Igari M, Abe T, Komatsu S, Nakano T, Kato S. Dose-volume parameters and local tumor control in cervical cancer treated with central-shielding external-beam radiotherapy and CT-based image-guided brachytherapy. J Radiat Res. 2019;60(4):490-500.
- Wakatsuki M, Kato S, Ohno T, Banu PA, Hoang NC, Yadamsuren E, Supriana N, Cao J, Devi CRB, Calaguas MJ, Chansilpa Y, Cho CK, Adylkhanov T, Okonogi N, Nakano T, Tsujii H. Multi-institutional Observational Study of Prophylactic Extended-Field Concurrent Chemoradiation Therapy Using Weekly Cisplatin for Patients With Pelvic Node-Positive Cervical Cancer in East and Southeast Asia.Int J Radiat Oncol Biol Phys. 2019;105(1):183-189.
- Kubo N, Kawamura H, Oike T, Sato H, Iwanaga M, Mizukami T, Adachi A, Matsui H, Ito K, Suzuki K, Nakano T. Hypofractionated Intensity-modulated Radiotherapy for Intermediate- and High-risk Prostate Cancer: A Retrospective Study. In Vivo. 2019;33(4):1235-1241.
- Matsui T, Oike T, Shirai K, Ohno T. Definitive Radiation Therapy for Merkel Cell Carcinoma Misdiagnosed as a Metastatic Tumor: A Case Report. Cureus. 2019;11(8):e5483.
- Shiba S, Shibuya K, Katoh H, Kaminuma T, Miyazaki M, Kakizaki S, Shirabe K, Ohno T, Nakano T. A comparison of carbon ion radiotherapy and transarterial chemoembolization treatment outcomes for single hepatocellular carcinoma: a propensity score matching study. Radiat Oncol. 2019;14(1):137.
- Shiba S, Okamoto M, Kiyohara H, Ohno T, Kaminuma T, Asao T, Ojima H, Shirabe K, Kuwano H, Nakano T. Prospective Observational Study of High-Dose Carbon-Ion Radiotherapy for Pelvic Recurrence of Rectal Cancer (GUNMA 0801). Front Oncol. 2019;9:702.
- Kubo N, Kubota Y, Kawamura H, Oike T, Sakai M, Kumazawa T, Miyasaka Y, Okazaki S, Kobayashi D, Sato H, Mizukami T, Musha A, Shirai K, Saitoh JI, Yokoo S, Chikamatsu K, Ohno T, Nakano T. Dosimetric parameters predictive of nasolacrimal duct obstruction after carbon-ion radiotherapy for head and neck carcinoma. Radiother Oncol. 2019;141:72-77.
- Shirai K, Kubota Y, Ohno T, Saitoh JI, Abe T, Mizukami T, Mori Y, Kawamura H, Akahane K, Nakano T. Carbon-ion Radiotherapy for Isolated Lymph Node Metastasis After Surgery or Radiotherapy for Lung Cancer. Front Oncol. 2019;9:731.
- Kobayashi D, Okonogi N, Wakatsuki M, Miyasaka Y, Kiyohara H, Ohno T, Kato S, Nakano T, Kamada T. Impact of CT-based brachytherapy in elderly patients with cervical cancer. Brachytherapy. 2019;18(6):771-779.
- Kawamura H, Kubo N, Sato H, Miyasaka Y, Matsui H, Ito K, Suzuki K, Ohno T. Quality of life in prostate cancer patients receiving particle radiotherapy: A review of the literature. Int J Urol. 2020;27(1):24-29.
- Saitoh JI, Shirai K, Mizukami T, Abe T, Ebara T, Ohno T, Minato K, Saito R, Yamada M, Nakano T. Hypofractionated carbon-ion radiotherapy for stage I peripheral nonsmall cell lung cancer (GUNMA0701): Prospective phase II study. Cancer Med. 2019;8(15):6644-6650.
- Shibuya K, Ohno T, Katoh H, Okamoto M, Shiba S, Koyama Y, Kakizaki S, Shirabe K, Nakano T. A feasibility study of high-dose hypofractionated carbon ion radiation therapy using four fractions for localized hepatocellular carcinoma measuring 3 cm or larger. Radiother Oncol. 2019;132:230-235.
- Kobayashi D, Sato H, Saitoh JI, Oike T, Nakajima A, Noda SE, Kato S, Iwanaga M, Shimizu T, Nakano T. Efficacy and Feasibility of Salvage Re-Irradiation with CyberKnife for In-Field Neck Lymph Node Recurrence: A Retrospective Study. J Clin Med. 2019;8(11).
- Takayasu Y, Kubo N, Shino M, Nikkuni O, Ida S, Musha A, Takahashi K, Hirato J, Shirai K, Saitoh JI, Yokoo S, Chikamatsu K, Ohno T, Nakano T; Working Group on Head and Neck Tumors. Cancer Med. 2019;8(17):7227-7235.
- Shrestha S, Higuchi T, Shirai K, Tokue A, Shrestha S, Saitoh JI, Hirasawa H, Ohno T, Nakano T, Tsushima Y. Prognostic significance of semi-quantitative FDG-PET parameters in stage I non-small cell lung cancer treated with carbon-ion radiotherapy. Eur J Nucl Med Mol Imaging. 2020;47(5):1220-1227.
- Okonogi N, Wakatsuki M, Kato S, Murata H, Kiyohara H, Karasawa K, Ohno T, Tsuji H, Nakano T, Shozu M; Working Group of Gynecological Tumors. Significance of concurrent use of weekly cisplatin in carbon-ion radiotherapy for locally advanced adenocarcinoma of the uterine cervix: A propensity score-matched analysis. Cancer Med. 2020;9(4):1400-1408.
- Musha A, Fukata K, Saitoh JI, Shirai K, Abe T, Mizukami T, Kawashima M, Yokoo S, Chikamatsu K, Ohno T, Nakano T. Tongue surface model can predict radiation tongue mucositis due to intensity-modulated radiation therapy for head and neck cancer. Int J Oral Maxillofac Surg. 2020;49(1):44-50.
- Shiba S, Shibuya K, Kawashima M, Okano N, Kaminuma T, Okamoto M, Kubota Y, Nakano T, Ohno T. Comparison of Dose Distributions When Using Carbon Ion Radiotherapy Versus Intensity-modulated Radiotherapy for Hepatocellular Carcinoma With Macroscopic Vascular Invasion: A Retrospective Analysis. Anticancer Res. 2020;40(1):459-464.
- Kawamura H, Kubo N, Sato H, Mizukami T, Katoh H, Ishikawa H, Ohno T, Matsui H, Ito K, Suzuki K, Nakano T; Group for Genitourinary Tumors at Gunma University Heavy Ion Medical Center. Moderately hypofractionated carbon ion radiotherapy for prostate cancer; a prospective observational study "GUNMA0702". BMC Cancer. 2020;20(1):75.
- Miyasaka Y, Yoshimoto Y, Murata K, Noda SE, Ando K, Ebara T, Okonogi N, Kaminuma T, Yamada S, Ikota H, Yokoo H, Ohno T, Nakano T. Treatment outcomes of patients with adenocarcinoma of the uterine cervix after definitive radiotherapy and the prognostic impact of tumor-infiltrating CD8+ lymphocytes in pre-treatment biopsy specimens: a multi-institutional retrospective study. J Radiat Res. 2020;61(2):275-284.
- Matsui T, Okano N, Kawamura H, Oike T, Ohno T. Mild Hypofractionated Radiation Therapy for Merkel Cell Carcinoma. Cureus. 2020;12(1):e6786.
- Darwis NDM, Oike T, Kawamura H, Kawahara M, Kubo N, Sato H, Miyasaka Y, Katoh H, Ishikawa H, Matsui H, Miyazawa Y, Ito K, Suzuki K, Gondhowiardjo S, Nakano T, Ohno T. Kinetics of Prostate-Specific Antigen after Carbon Ion Radiotherapy for Prostate Cancer. Cancers (Basel). 2020;12(3).
Biology
- Nachankar A, Musha A, Kubo N, Kawamura H, Okano N, Sato H, Okada K, Adachi A, Ohno T. Dosimetric analysis of intraocular hemorrhage in nonsquamous head and neck cancers treated with carbon-ion radiotherapy. Radiother Oncol. 2022 May;170:143-150. doi: 10.1016/j.radonc.2022.02.032. Epub 2022 Mar 4. PMID: 35257851.
- Zhang S, Adachi T, Zhang S, Yoshida Y, Takahashi A. A new type of simulated partial gravity apparatus for rats based on a pully-spring system Front Cell Dev Biol. 2022 Aug 31;10:965656. doi: 10.3389/fcell.2022.965656. eCollection 2022.
- Ju Z, Thomas TN, Chiu YJ, Yamanouchi S, Yoshida Y, Abe JI, Takahashi A, Wang J, Fujiwara K, Hada M. Adaptation and Changes in Actin Dynamics and Cell Motility as Early Responses of Cultured Mammalian Cells to Altered Gravitational Vector Int J Mol Sci. 2022 May 30;23(11):6127. doi: 10.3390/ijms23116127.
- Puspitasari A, Squarcio F, Quartieri M, Totis C, Hitrec T, Takahashi A, Yoshida Y, Hanamura K, Yako T, Cerri M, Simoniello P, Durante M, Tinganelli W. Synthetic torpor protects rats from exposure to accelerated heavy ions Sci Rep. 2022 Sep 30;12(1):16405. doi: 10.1038/s41598-022-20382-6.
- Hirayama J, Hattori A, Takahashi A, Furusawa Y, Tabuchi Y, Shibata M, Nagamatsu A, Yano S, Maruyama Y, Matsubara H, Sekiguchi T, Suzuki N. Physiological consequences of space flight, including abnormal bone metabolism, space radiation injury, and circadian clock dysregulation: Implications of melatonin use and regulation as a countermeasure J Pineal Res. 2023 Jan;74(1):e12834. doi: 10.1111/jpi.12834. Epub 2022 Oct 17.
- Nachankar A, Oike T, Hanaoka H, Kanai A, Sato H, Yoshida Y, Obinata H, Sakai M, Osu N, Hirota Y, Takahashi A, Shibata A, Ohno T. 64Cu-ATSM Predicts Efficacy of Carbon Ion Radiotherapy Associated with Cellular Antioxidant Capacity. Cancers 13 24 6159 doi:10.3390/cancers13246159
- Kumazawa T, Mori Y, Sato H, Permata TBM, Uchihara Y, Noda SE, Okada K, Kakoti S, Suzuki K, Ikota H, Yokoo H, Gondhowiardjo S, Nakano T, Ohno T, Shibata A. Expression of non-homologous end joining factor, Ku80, is negatively correlated with PD-L1 expression in cancer cells after X-ray irradiation. Oncology Letters, 2022;23(1):29.
- Permata TBM, Sato H, Gu W, Kakoti S, Uchihara Y, Yoshimatsu Y, Sato I, Kato R, Yamauchi M, Suzuki K, Oike T, Tsushima Y, Gondhowiardjo S, Ohno T, Yasuhara T, Shibata A. High linear energy transfer carbon-ion irradiation upregulates PD-L1 expression more significantly than X-rays in human osteosarcoma U2OS cells. Journal of Radiation Research, 62(5):773-781, 2021.
- Uchihara Y, Permata TBM, Sato H, Shibata A. Modulation of immune responses by DNA damage signaling. DNA Repair. 2021;104:103135.
- Mori Y, Sato H, Kumazawa T, Permata TBM, Yoshimoto Y, Murata K, Noda SE, Kaminuma T, Ando K, Oike T, Okonogi N, Okada K, Kakoti S, Suzuki K, Ikota H, Yokoo H, Nakano T, Ohno T, Shibata A. Analysis of radiotherapy‑induced alteration of CD8+ T cells and PD‑L1 expression in patients with uterine cervical squamous cell carcinoma. Oncology Letters, 2021;21(6):446.
- Osu N, Makinoshima H, Oike T, Ohno T. Metabolic alteration in cancer cells bytherapeutic carbon ions. Anticancer Research 2021;41:6023–6029.
- Oike T, Ohno T. Molecular mechanisms underlying radioresistance: data compiled from isogenic cell experiments. Ann Transl Med 2020;8(6):273.
- Osu N, Kobayashi D, Shirai K, Musha A, Sato H, Hirota Y, Shibata A, Oike T, Ohno T. Relative Biological Effectiveness of Carbon Ions for Head-and-Neck Squamous Cell Carcinomas According to Human Papillomavirus Status. J Pers Med 2020;10(3):71.
- Oike T, Komatsu S, Komatsu Y, Nachankar A, Darwis NDM, Shibata A, Ohno T. Reporting of methodologies used for clonogenic assays to determine radiosensitivity. J Radiat Res 2020;61(6):828-831.
- Kobayashi D, Oike T, Murata K, Irie D, Hirota Y, Sato H, Shibata A, Ohno T. Induction of Micronuclei in Cervical Cancer Treated with Radiotherapy. J Pers Med 2020;10(3):110.
- Oike T, Hirota Y, Dewi Maulany Darwis N, Shibata A, Ohno T. Comparison of Clonogenic Survival Data Obtained by Pre- and Post-Irradiation Methods. J Pers Med 2020;10(4):171.
- Shiba S, Wakatsuki M, Ohno T, Nakano T. Differences in Linear Energy Transfer Affect Cell-killing and Radiosensitizing Effects of Spread-out Carbon-ion Beams. Anticancer Res 2020;40(10):5497-5502.
- Takahashi A, Yamanouchi S, Takeuchi K, Takahashi S, Tashiro M, Hidema J, Higashitani A, Adachi T, Zhang S, Guirguis FNL, Yoshida Y, Nagamatsu A, Hada M, Takeuchi K, Takahashi T, Sekitomi Y. Combined Environment Simulator for Low-Dose-Rate Radiation and Partial Gravity of Moon and Mars. Life 2020;10(11):274.
- Yamanouchi S, Rhone J, Mao JH, Fujiwara K, Saganti PB, Takahashi A, Hada M. Simultaneous exposure of cultured human lymphoblastic cells to simulated microgravity and radiation increases chromosome aberrations. Life (Basel) 2020;10:187.
- Ma L, Sakamoto Y, Kanai A, Otsuka H, Takahashi A, Kakimi K, Imai T, Shimokawa T. Characterization of a novel murine colon carcinoma subline with high-metastatic activity established by in vivo selection method. Int J Mol Sci 2020;21:2829.
- Kim EH, Kim JY, Kim MS, Vares G, Ohno T, Takahashi A, Uzawa A, Seo SJ, Sai S. Molecular mechanisms underlying the enhancement of carbon ion beam radiosensitivity of osteosarcoma cells by miR-29b. Am J Cancer Res 2020;10:4357-4371.
- Kim EH, Kim MS, Takahashi A, Suzuki M, Vares G, Uzawa A, Fujimori A, Ohno T, Sai S. Carbon-ion beam irradiation alone or in combination with zoledronic acid effectively kills osteosarcoma cells. Cancers (Basel) 2020;12:698.
- Ito SS, Nakagawa Y, Matsubayashi M, Sakaguchi YM, Kobashigawa S, Matsui TK, Nanaura H, Nakanishi M, Kitayoshi F, Kikuchi S, Kajihara A, Tamaki S, Sugie K, Kashino G, Takahashi A, Hasegawa M, Mori E, Kirita T. Inhibition of the ATR kinase enhances 5-FU sensitivity independently of nonhomologous end-joining and homologous recombination repair pathways. J Biol Chem 2020;295:12946-12961.
- Puspitasari A, Yamazaki H, Kawamura H, Nakano T, Takahashi A, Shirao T, Held KD. Xirradiation of developing hippocampal neurons causes changes in neuron population phenotypes, dendritic morphology and synaptic protein expression in surviving neurons at maturity. Neurosci Res 2020;160:11-24.
- Furukawa S, Nagamatsu A, Nenoi M, Fujimori A, Kakinuma S, Katsube T, Wang B, Tsuruoka C, Shirai T, Nakamura AJ, Sakaue-Sawano A, Miyawaki A, Harada H, Kobayashi M, Kobayashi J, Kunieda T, Funayama T, Suzuki M, Miyamoto T, Hidema J, Yoshida Y, Takahashi A. Space radiation biology for “Living in Space”. BioMed Res Int. 2020; 4703286:2020.
- Ito SS, Nakagawa Y, Matsubayashi M, Sakaguchi YM, Kobashigawa S, Matsui TK, Nanaura H, Nakanishi M, Kitayoshi F, Kikuchi S, Kajihara A, Tamaki S, Sugie K, Kashino G, Takahashi A, Hasegawa M, Mori E, Kirita T. Inhibition of the ATR kinase enhances 5-FU sensitivity independently of non-homologous end-joining and homologous recombination repair pathways. J Biol Chem. 2020, doi: 10.1074/jbc.RA120.013726.
- Ma L, Sakamoto Y, Kanai A, Otsuka H, Takahashi A, Kakimi K, Imai T, Shimokawa T. Characterization of a novel murine colon carcinoma subline with high-metastatic activity established by in vivo selection method. Int J Mol Sci. 2020; 21: 2829.
- Kim EH, Kim MS, Takahashi A, Suzuki M, Vares G, Uzawa A, Fujimori A, Ohno T, Sai S. Carbon-ion beam irradiation alone or in combination with zoledronic acid effectively kills osteosarcoma cells. Cancers. 2020;12:698.
- Anakura M, Nachankar A, Kobayashi D, Amornwichet N, Hirota Y, Shibata A, Oike T, Nakano T. Radiosensitivity Differences between EGFR Mutant and Wild-Type Lung Cancer Cells are Larger at Lower Doses. Int J Mol Sci. 2019;20(15).
- Komatsu S, Oike T, Komatsu Y, Kubota Y, Sakai M, Matsui T, Nuryadi E, Permata TBM, Sato H, Kawamura H, Okamoto M, Kaminuma T, Murata K, Okano N, Hirota Y, Ohno T, Saitoh JI, Shibata A, Nakano T. Deep learning-assisted literature mining for in vitro radiosensitivity data. Radiother Oncol. 2019;139:87-93.
- Matsui T, Nuryadi E, Komatsu S, Hirota Y, Shibata A, Oike T, Nakano T. Robustness of Clonogenic Assays as a Biomarker for Cancer Cell Radiosensitivity. Int J Mol Sci. 2019;20(17).
- Darwis NDM, Nachankar A, Sasaki Y, Matsui T, Noda SE, Murata K, Tamaki T, Ando K, Okonogi N, Shiba S, Irie D, Kaminuma T, Kumazawa T, Anakura M, Yamashita S, Hirakawa T, Kakoti S, Hirota Y, Tokino T, Iwase A, Ohno T, Shibata A, Oike T, Nakano T. FGFR Signaling as a Candidate Therapeutic Target for Cancers Resistant to Carbon Ion Radiotherapy. Int J Mol Sci. 2019;20(18).
- Kakoti S, Yamauchi M, Gu W, Kato R, Yasuhara T, Hagiwara Y, Laskar S, Oike T, Sato H, Held KD, Nakano T, Shibata A. p53 deficiency augments nucleolar instability after ionizing irradiation. Oncol Rep. 2019;42(6):2293-2302.
- Hagiwara Y, Oike T, Niimi A, Yamauchi M, Sato H, Limsirichaikul S, Held KD, Nakano T, Shibata A. Clustered DNA double-strand break formation and the repair pathway following heavy-ion irradiation. J Radiat Res. 2019;60(1):69-79.
- Puspitasari A, Yamazaki H, Kawamura H, Nakano T, Takahashi A, Shirao T, Held KD. X-irradiation of developing hippocampal neurons causes changes in neuron population phenotypes, dendritic morphology and synaptic protein expression in surviving neurons at maturity. Neurosci Res. 2019: S0168-0102(19)30320-7.
- Hada M, Ikeda H, Rhone JR, Beitman AJ, Plante I, Souda H, Yoshida Y, Held KD, Fujiwara K, Saganti PB, Takahashi A. Increased chromosome aberrations in cells exposed simultaneously to simulated microgravity and radiation. Int J Mol Sci. 2019;20:43.
- Masunaga SI, Tano K, Sanada Y, Suzuki M, Takahashi A, Ohnishi K, Ono K. Effects of p53 Status of Tumor cells and combined treatment with mild hyperthermia, wortmannin or caffeine on recovery from radiation-induced damage. World J Oncol. 2019;10(3):132-141.
- Ma L, Kambe R, Tsuchiya T, Kanegasaki S, Takahashi A. Anti-metastatic benefits produced by hyperthermia and a CCL3 derivative. Cancers (Basel). 2019;11(11):E1770.
- Ikeda H, Muratani M, Hidema J, Hada M, Fujiwara K, Souda H, Yoshida Y, Takahashi A. Expression profile of cell cycle-related genes in human fibroblasts exposed simultaneously to radiation and simulated microgravity. Int J Mol Sci. 2019;20(19):E4791.
- Ikegame M, Hattori A, Tabata MJ, Kitamura KI, Tabuchi Y, Furusawa Y, Maruyama Y, Yamamoto T, Sekiguchi T, Matsuoka R, Hanmoto T, Ikari T, Endo M, Omori K, Nakano M, Yashima S, Ejiri S, Taya T, Nakashima H, Shimizu N, Nakamura M, Kondo T, Hayakawa K, Takasaki I, Kaminishi A, Akatsuka R, Sasayama Y, Nishiuchi T, Nara M, Iseki H, Chowdhury VS, Wada S, Ijiri K, Takeuchi T, Suzuki T, Ando H, Matsuda K, Somei M, Mishima H, Mikuni-Takagaki Y, Funahashi H, Takahashi A, Watanabe Y, Maeda M, Uchida H, Hayashi A, Kambegawa A, Seki A, Yano S, Shimazu T, Suzuki H, Hirayama J, Suzuki N. Melatonin is a potential drug for the prevention of bone loss during space flight. J Pineal Res. 2019;67(3):e12594.
- Oh JT, Kim EH, Lee YJ, Sai S, Lim SH, Park JW, Chung HK, Kim J, Vares G, Takahashi A, Jeong YK, Kim MS, Kong C-B. Synergistic autophagy effect of miR 212-3p in zoledronic acid-treated in vitro and orthotopic in vivo models and in patient-derived osteosarcoma cells. Cancers. 2019;11:1812.
- Takahashi A, Wakihata A, Ma L, Adachi T, Hirose H, Yoshida Y, Ohira Y. "Temporary Loading Prevents Cancer Progression and Immune Organ Atrophy Induced by Hind-Limb Unloading in Mice". Int J Mol Sci. 19, 3959, 2018
- Yoshida Y, Tominaga S, Ma J, Takahashi A. "Heat induces histone γH2AX gormation under hypoxia". Theram Med, 34(3), 45-51, 2018
- Takahashi A, Yoshida Y, Wakihata S, Ohira Y. "Combination effects of space radiation and zero-gravity". Gekkan Saibou. 50(12), 640-643, 2018
- Takahashi A, Ikeda H, Yoshida Y. "Role of high-linear energy transfer radiobiology in space radiation exposure risks". Int J Particle Ther. 5(1), 151-159, 2018
- Yoshida Y, Sejimo Y, Kurachi M, Ishizaki Y, Nakano T, Takahashi A. "X-ray irradiation induces disruption of the blood brain barrier with localized changes in claudin-5 and activation of microglia in the mouse brain", Neurochem Int, 2018;119:199-206
- Nakagawa Y, Kajihara A, Takahashi A, Murata AS, Matsubayashi M, Ito SS, Ota I, Nakagawa T, Hasegawa M, Kirita T, Ohnishi T, Mori E. "BRCA2 protects mammalian cells from heat shock", Int J Hyperthermia, 2018;34(6):795-801
- Park SJ, Heo K, Choi C, Yang K, Adachi A, Okada H, Yoshida Y, Ohno T, Nakano T, Takahashi A. "Carbon ion irradiation abrogates Lin28B-induced X-ray resistance in melanoma cells", J Radiat Res, 2017;58(6),765-71
- Ikeda H, Souda H, Puspitasari A, Held KD, Hidema J, Nikawa T, Yoshida Y, Kanai T, Takahashi A. , "Development and performance evaluation of a three-dimensional clinostat synchronized heavy-ion irradiation system", Life Sci Space Res, 12, 51-60, 2017
- Ikeda H, Souda H, Puspitasari A, Held KD, Hidema J, Nikawa T, Yoshida Y, Kanai T, Takahashi A. , "A new system for three-dimensional clinostat synchronized x-irradiation with a high-speed shutter for space radiation research", Biol Sci Space, 30, 8-16, 2016
- Held KD, Kawamura H, Kaminuma T, Paz AES, Yoshida Y, Willers H, Takahashi A, "Effects of charged particles on human tumor cells", Frontiers Oncol, 6, 23, 2016
- Takahashi A, "Molecular damage: Hyperthermia alone", Hyperthermic Oncology from Bench to Besides, , 19-32, 2016
- Takahashi A, "Inhibition of DNA repair system activity", Hyperthermic Oncology from Bench to Besides, , 91-108, 2016
- Takahashi A, Mori E, Nakagawa Y, Kajihara A, Kirita T, Pittman LD, Hasegawa M, Ohnishi T, "Homologous recombination preferentially repairs heat-induced DNA double-strand breaks in mammalian cells", Int J Hyperthermia, 13, 1-7, 2016
- Ando K, Fujita H, Hosoi A, Ma L, Wakatsuki M, Seino KI, Kakimi K, Imai T, Shimokawa T, Nakano T., "Intravenous dendritic cell administration enhances suppression of lung metastasis induced by carbon-ion irradiation", JOURNAL OF RADIATION RESEARCH, 27, 1-10, 2016
- Ando K, Goodhead DT., "Dependence and independence of survival parameters on linear energy transfer in cells and tissues", JOURNAL OF RADIATION RESEARCH, 57, 596-606, 2016
- Kobayashi D, Oike T, Shibata A, Niimi A, Kubota Y, Sakai M, Amornwhichet N, Yoshimoto Y, Hagiwara Y, Kimura Y, Hirota Y, Sato H, Isono M, Yoshida Y, Kohno T, Ohno T, Nakano T., "Mitotic catastrophe is a putative mechanism underlying the weak correlation between sensitivity to carbon ions and cisplatin.", Scientific reports, 7, 40588, 2016
- Isono M, Niimi A, Oike T, Hagiwara Y, Sato H, Sekine R, Yoshida Y, Isobe SY, Obuse C, Nishi R, Petricci E, Nakada S, Nakano T, Shibata A., "BRCA1 Directs the Repair Pathway to Homologous Recombination by Promoting 53BP1 Dephosphorylation.", Cell reports, 18, 520-532, 2016
- Takayasu Y, Shino M, Nikkuni O, Yoshida Y, Furuya N, Chikamatsu K., "Oxygen-glucose deprivation increases firing of unipolar brush cells and enhances spontaneous EPSCs in Purkinje cells in the vestibulo-cerebellum.", Neuroscience research, 106, 1-11, 2016
Physics
- Varnava M, Musha A, Tashiro M, Kubo N, Okano N, Kawamura H, Ohno T. Dose-volume constraints for head-and-neck cancer in carbon ion radiotherapy: A literature review. Cancer Med. 2023. https://doi.org/10.1002/cam4.5641. Epub ahead of print.
- Tashiro M, Kawashima M. Linear energy transfer-independent calibration of radiochromic film for carbon-ion beams. Physics and Imaging in Radiation Oncology 23 140-143. DOI: 10.1016/j.phro.2022.08.001
- Parajuli RK, Sakai M, Parajuli R, Tashiro M. Development and Applications of Compton Camera-A Review Sensors (Basel). 2022 Sep 28;22(19):7374. doi: 10.3390/s22197374.
- Li Y, Sakai M, Tsunoda A, Kubo N, Kitada Y, Kubota Y, Matsumura A, Zhou Y, Ohno T. Normal Tissue Complication Probability Model for Acute Radiation Dermatitis in Patients With Head and Neck Cancer Treated With Carbon Ion Radiation Therapy Int J Radiat Oncol Biol Phys. 2022 Jul 1;113(3):675-684. doi: 10.1016/j.ijrobp.2022.03.002. Epub 2022 Mar 9.
- Tashiro M, Yoshida Y, Oike T, Nakao M, Yusa K, Hirota Y, Ohno T. First Human Cell Experiments With FLASH Carbon Ions. Anticancer Res. 2022;42(5):2469-2477. doi: 10.21873/anticanres.15725.
- Kawashima M, Tashiro M, Varnava M, Shiba S, Matsui T, Okazaki S, Li Y, Komatsu S, Kawamura H, Okamoto M, Ohno T. "An adaptive planning strategy in carbon ion therapy of pancreatic cancer involving beam angle selection." Phys Imaging Radiat Oncol. 2022;21:35-41.
- Fukata K, Kawamura H, Kubo N, Kanai T, Torikoshi M, Nakano T, Tashiro M, Ohno T. Retrospective comparison of rectal toxicity between carbon-ion radiotherapy and intensity-modulated radiation therapy based on treatment plan, normal tissue complication probability model, and clinical outcomes in prostate cancer. Phys Med. 2021 Oct;90:6-12. doi: 10.1016/j.ejmp.2021.08.013.
- Li Y, Kubota Y, Okamoto M, Shiba S, Okazaki S, Matsui T, Tashiro M, Nakano T, Ohno T. Adaptive planning based on single beam optimization in passive scattering carbon ion radiotherapy for patients with pancreatic cancer. Radiat Oncol. 2021 Jun 19;16(1):111. doi: 10.1186/s13014-021-01841-2.
- Parajuli RK, Sakai M, Arakawa K, Kubota Y, Kubo N, Tashiro M. Carbon range verification with 718 keV Compton imaging. Scientific Reports 11 1 doi:10.1038/s41598-021-00949-5
- Zhou Y, Li Y, Kubota Y, Sakai M, Ohno T. Robust Angle Selection in Particle Therapy Frontiers in Oncology 2021; 11 doi:10.3389/fonc.2021.715025
- 酒井真理.群馬大学におけるコンプトンカメラの研究開発 MEDICAL IMAGING TECHNOLOGY 2021; 39 5 211
- 山口皐平, 柳澤理央, 大木佑哉, 酒井真理, 松村彰彦, 加田渉.重粒子線がん治療場での臨床線量の評価を目的とした半導体線量計の開発 BIO INDUSTRY 2022; 39(1): 31.
- 田代 睦. 群馬大学重粒子線医学研究センターの紹介. 医学物理, 2021; 41(3): 161-165.
- Sakai M, Parajuli RK, Kubota Y, Kubo N, Yamaguchi M, Nagao Y, Kawachi N, Kikuchi M, Arakawa K, Tashiro M. Crosstalk Reduction Using a Dual Energy Window Scatter Correction in Compton Imaging. Sensors (Basel) 2020;20(9):2453.
- Shiba S, Parajuli RK, Sakai M, Oike T, Ohno T, Nakano T. Use of a Si/CdTe Compton Camera for In vivo Real-Time Monitoring of Annihilation Gamma Rays Generated by Carbon Ion Beam Irradiation. Front Oncol 2020;10:635.
- Kawashima M, Matsumura A, Souda H, Tashiro M. Simultaneous determination of the dose and linear energy transfer (LET) of carbon-ion beams using radiochromic films. Phys Med Biol. 2020;65(12):125002.
- Yokoyama A, Kubota Y, Kawamura H, Miyasaka Y, Kubo N, Sato H, Abe S, Tsuda K, Sutou T, Ohno T, Nakano T. Impact of Inter-fractional Anatomical Changes on Dose Distributions in Passive Carbon-Ion Radiotherapy for Prostate Cancer: Comparison of Vertical and Horizontal Fields. Front Oncol 2020;10:1264.
- Tashiro M, Souda H, Yoshida T, Sakurai H. Reconstruction of dose distributions for fine carbon-ion beams using iterative approximation toward carbon-knife. Phys Med Biol 2020;65(22):225023.
- Kubota Y, Okamoto M, Shiba S, Okazaki S, Matsui T, Li Y, Itabashi Y, Sakai M, Kubo N, Tsuda K, Ohno T, Nakano T. Robustness of daily dose for each beam angle and accumulated dose for inter-fractional anatomical changes in passive carbon-ion radiotherapy for pancreatic cancer: Bone matching versus tumor matching. Radiother Oncol 2021;157:85-92.
- Li Y, Kubota Y, Okamoto M, Shiba S, Okazaki S, Matsui T, Komatsu S, Ohno T. Determination of Deformable Image Registration Algorithms for Accumulating Dose in Carbon-ion Radiotherapy for Pancreatic Cancer. Anticancer Res 2021;41(2):835-843.
- Lee SH, Sunaguchi N, Nagao A, Hirano Y, Sakurai H, Kano Y, Torikoshi M, Kanai T, Tashiro M. Calculation of Stopping-Power Ratio from Multiple CT Numbers Using Photon-Counting CT System: Two- and Three-Parameter-Fitting Method. Sensors (Basel) 2021;21(4):1215.
- Sakai M, Kubota Y, Kubo N, Tashiro M Evaluating the Certification Examination for Medical Physicists in Japan Via Questionnaire Survey and Access Analyses. Kitakanto Med J 2020;70(4):379-385
- Yamaguchi M, Yamamoto S, Kitano M, Kubota Y, Sakai M, Akagi T, Nagao Y, Kawachi N Estimation of shifts of therapeutic carbon-ion beams owing to cavities in a polyethylene target by measuring prompt X-ray images. Jpn J Appl Phys 2020;59:87001
- Kubota Y, Ohno T, Kawashima M, Murata K, Okonogi N, Noda SE, Tsuda K, Sakai M, Tashiro M, Nakano T. Development of a Vaginal Immobilization Device: A Treatment-planning Study of Carbon-ion Radiotherapy and Intensity-modulated Radiation Therapy for Uterine Cervical Cancer. Anticancer Res. 2019;39(4):1915-1921.
- Kubota Y, Katoh H, Shibuya K, Shiba S, Abe S, Sakai M, Yuasa D, Tsuda K, Ohno T, Nakano T. Comparison between bone matching and marker matching for evaluation of intra- and inter-fractional changes in accumulated dose of carbon ion radiotherapy for hepatocellular carcinoma. Radiother Oncol. 2019;137:77-82.
- Tashiro M, Kubota Y, Torikoshi M, Ohno T, Nakano T. Divided-volume matching technique for volume displacement estimation of patient positioning in radiation therapy. Phys Med. 2019:62;1-12.
- Itabashi Y, Kubota Y, Okamoto M, Tsuda K, Shiba S, Hoshino Y, Suto T, Ohno T, Nakano T. Potential Pitfalls of Diaphragm Structural Matching in Carbon-ion Radiotherapy for Pancreatic Cancer. Anticancer Res. 2019;39(8):4351-4356.
- Sakai M, Kubota Y, Parajuli RK, Kikuchi M, Arakawa K, Nakano T. Compton imaging with 99mTc for human imaging. Sci Rep. 2019;9(1):12906.
- Kubota Y, Okamoto M, Li Y, Shiba S, Okazaki S, Komatsu S, Sakai M, Kubo N, Ohno T, Nakano T. Evaluation of Intensity- and Contour-Based Deformable Image Registration Accuracy in Pancreatic Cancer Patients. Cancers (Basel). 2019;11(10).
- Kada W, Sudić I, Skukan N, Kawabata S, Satoh T, Susaki J, Yamada S, Sekine T, Parajuli RK, Sakai M, Miura K, Koka M, Yamada N, Kamiya T, Jakšić M, Hanaizumi O. Evaluation of scintillation properties of α- and β-SiAlON phosphors under focused microbeam irradiation using ion-beam-induced luminescence analysis. Nucl Instrum Meth B. 2019;450:157-162.
- Li Y, Kubota Y, Kubo N, Mizukami T, Sakai M, Kawamura H, Irie D, Okano N, Tsuda K, Matsumura A, Saitoh JI, Nakano T, Ohno T. Dose assessment for patients with stage I non-small cell lung cancer receiving passive scattering carbon-ion radiotherapy using daily computed tomographic images: A prospective study. Radiother Oncol. 2020;144:224-230.
- Yamaguchi M, Sakai M, Nagao Y, Kikuchi M, Arakawa K, Kawachi N. A novel estimation method of water-equivalent thicknesses of secondary particle tracks using secondary electron bremsstrahlung emitted from therapeutic ion beams for attenuation correction. Nucl Instrum Meth A. 2020;954:161607
- Nakano T, Sakai M, Torikai K, Suzuki Y, Takeda S, Noda SE, Yamaguchi M, Nagao Y, Kikuchi M, Odaka H, Kamiya T, Kawachi N, Watanabe S, Arakawa K, Takahashi T. Imaging of 99mTc-DMSA and 18F-FDG in humans using a Si/CdTe Compton camera. Phys Med Biol. 2020;65(5):05LT01.
- Sakai M, Parajuli RK, Kubota Y, Kubo N, Kikuchi M, Arakawa K, Nakano T. Improved iterative reconstruction method for Compton imaging using median filter. PLoS One. 2020;15(3):e0229366.
- Li Y, Kubota Y, Tashiro M, Ohno T. "Value of Three-Dimensional Imaging Systems for Image-Guided Carbon Ion Radiotherapy". Cancers. 11, 296, 2019
- Sakai M, Parajuli RK, Kikuchi M, Yamaguchi M, Nagao Y, Kawachi N, Arakawa K, Nakano T. "Effect of number of views on cross-sectional Compton imaging: A fundamental study with backprojection". Phys Med. 56, 1–9, 2018
- Hirano Y, Kodaira S, Souda H, Matsumura A, Torikoshi M. "Linear energy transfer (LET) spectra and survival fraction distribution based on the CR-39 plastic charged-particle detector in a spread-out Bragg peak irradiation by a 12C beam". Phys Med Biol. 63:185006, 2018
- Sakai M, Yamaguchi M, Nagao Y, Kawachi N, Kikuchi M, Torikai K, Kamiya T, Takeda S, Watanabe S, Takahashi T, Arakawa K, Nakano T. "In vivo simultaneous imaging with 99mTc and 18F using a Compton camera". Phys Med Biol. 63(20):205006, 2018
- Paz A, Yamamoto N, Sakama M, Matsufuji N, Kanai T. "Tumor control probability analysis for single fraction carbon ion radiotherapy of early-stage non-small cell lung cancer". Int J Radiat Oncol Biol Phys. 102(5), 1551–1559, 2018
- Lee SH, Sunaguchi N, Hirano Y, Kano Y, Liu C, Torikoshi M, Ohno T, Nakano T, Kanai T. "A carbon CT system: how to obtain accurate stopping power ratio using a Bragg peak reduction technique". Phys Med Biol. 63 035025, 2018
- Sakai M, Kubota Y, Saitoh J, Irie D, Shirai K, Okada R, Torikoshi M, Ohno T, Nakano T, "Robustness of patient positioning for inter-fractional error in carbon ion radiotherapy for stage I lung cancer: bone matching versus tumor matching", Radiotherapy and Oncology, 129, 95–100, 2018
- Hirano Y, Kodaira S, Souda H, Matsumura A, Torikoshi M, Linear energy transfer (LET) spectra and survival fraction distributionbased on the CR-39 plastic charged-particle detector in a spread-out Bragg peak irradiation by a 12C beam, Phys Med Biol. 2018;63(18):185006
- Bridges D, Kawamura H, Kanai T. "Probabilistic dose distribution from interfractional motion in carbon ion radiation therapy for prostate cancer shows rectum sparing with moderate target coverage degradation ". PLoS One. 2018;13(8):e0203289
- Keawsamur M, Matsumura A, Souda H, Kano Y, Torikoshi M, Nakano T, Kanai T. "Development of stereotactic radiosurgery using carbon beams (carbon-knife)". Phys Med Biol 2018;63(4):045024.
- Kubota Y, Sakai M, Tashiro M, Saitoh J, Abe T, Ohno T, Nakano T. "Technical Note: Predicting dose distribution with replacing stopping power ratio for inter-fractional motion and intra-fractional motion during carbon ion radiotherapy with passive irradiation method for stage I lung cancer". Med Phys 2018;45(7):3453-3441.
- Yamaguchi M, Nagao Y, Ando K, Yamamoto S, Sakai M, Parajuli RK, Arakawa K, Kawachi N. "Imaging of monochromatic beams by measuring secondary electron bremsstrahlung for carbon-ion therapy using a pinhole x-ray camera", Phys Med Biol 2018;63:045016.
- Kubota Y, Hayashi H, Abe S, Souda S, Okada R, Ishii T, Tashiro M, Torikoshi M, Kanai T, Ohno T, Nakano T. "Evaluation of the accuracy and clinical practicality of a calculation system for patient positional displacement in carbon ion radiotherapy at five sites", J Appl Clin Med Phys 2018;19:144-153.
- Tajiri S, Tashiro M, Mizukami T, Tsukishima C, Torikoshi M, Kanai T. Margin estimation and disturbances of irradiation field in layer-stacking carbon-ion beams for respiratory moving targets. Journal of Radiation Research, 58, 840-848, 2017.
- S Abe, Y Kubota, K Shibuya, Y Koyama, T Abe, T Ohno, T Nakano, "Fiducial marker matching versus vertebral body mathching: dosimetric impact of patient positioning in carbon ion radiotherapy for primary hepatic cancer", Physica Medica, 33, 114-120, 2017.
- Houweling AC, Fukata K, Kubota Y, Shimada H, Rasch CR, Ohno T, Bel A, van der Horst A, "The impact of interfractional anatomical changes on the accumulated dose in carbon ion therapy of pancreatic cancer patients", Radiotherapy and Oncology, 119(2), 319-25, 2016
- Kubota Y, Kawamura H, Sakai M, Tsumuraya R, Tashiro M, Yusa K, Kubo N, Sato H, Kawahara M, Katoh H, Kanai T, Ohno T, Nakano T., "Changes in Rectal Dose Due to Alterations in Beam Angles for Setup Uncertainty and Range Uncertainty in Carbon-Ion Radiotherapy for Prostate Cancer", PLoS One, 11(4), e0153894, 2016
- Yamaguchi M, Nagao Y, Kawachi N, Satoh T, Fujimaki S, Kamiya T, Torikai K, Shimada H, Sugai H, Sakai M, Arakawa K, Nakano T, "Detection of a gas region in a human body across a therapeutic carbon beam by measuring low-energy photons", I.J.PIXE, 26(01n02), 61-72, 2016
- Y Kurosawa, Y Kubota, E Takeshita, R Okada, Y Ohashi, H Souda, T Ishii, T Sutou, T Kanai, T Ohno, T Nakano, A Novel Evaluation Method for Displacement between Carbon Beam Axis and Positioning X-ray Axis Using an Imaging Plate, Nihon Hoshasen Gijutsu Gakkai Zasshi, 72(2), 139-148, 2016
- N Mogi, M Sakai, R Okada, Itabashi, H Fukushima, Y Kubota, T Sutou, T Nakano, T Ohno, The impact of gadolinium-based contrast agent for carbon ion radiotherapy. Nihon Hoshasen Gijutsu Gakkai Zasshi, 72(12), 1230-1236. 2016.
- Matsumura A, Yusa K, Kanai T, Mizota M, Ohno T, Nakano T, Evaluation of an empirical monitor output estimation in carbon ion radiotherapy. Medical Physics 42, 5188-5194, 2015.
- Tashiro M, Ishii T, Koya J, Okada R, Kurosawa Y, Arai K, Abe S, Ohashi Y, Shimada H, Yusa K, Kanai T, Yamada S, Kawamura H, Ebara T, Ohno T, Nakano T. Technical approach to individualized respiratory-gated carbon-ion therapy for mobile organs. Radiological Physics and Technology, 6, 356-366, 2013.
- Sakama M, Kanai T, Kase Y, Yusa K, Tashiro M, Torikai K, Shimada H, Yamada S, Ohno T, Nakano T. Design of ridge filters for spread-out Bragg peaks with Monte Carlo simulation in carbon ion therapy. Phys Med Biol 57: 6615-6633, 2012.
- Tashiro M, Minohara S, Kanai T, Yusa K, Sakurai H, Nakano T. Three-dimensional velocity mapping of lung motion using vessel bifurcation pattern matching. Medical Physics, 33, 1747-1757, 2006.
Award
- 武者 篤, 令和3年度日本歯科放射線学会 学術奨励賞, 2022年6月
- 武者 篤, 第76回日本口腔科学会学術集会 学会賞優秀ポスター賞, 2022年6月
- 宮坂 勇平, 第60回日本癌治療学会学術集会 Young Oncologist Award, 2022年10月
- 柴 慎太郎, 第60回日本癌治療学会学術集会 Young Oncologist Award, 2022年10月
- 安藤 謙, 第60回日本癌治療学会学術集会 Young Oncologist Awardb, 2022年10月
- Fady Nagy, 群馬大学学業最優秀賞(学長表彰), 2022.03.23
- 小林 優斗, 学業優秀賞(医学系研究科長表彰), 2022.03.23
- 武者 篤. 日本放射線腫瘍学会 2021年梅垣賞
- 武者 篤. 群馬イノベーションアワード2021 ファイナリスト
- 酒井 真理. 医療用コンプトンカメラの開発 ぐんまテックプランター2021 群馬銀行賞
- Tashiro M. Radiological Physics and Technology. Outstanding Reviewer Award. 2021
- 髙橋 昭久, One of the Most Valued Reviewers from 2021 2022.03.03
- 山之内 佐久也, 第68回北関東医学会総会 優秀発表賞 2021.09.30
- 山之内 佐久也, 日本宇宙生物科学会第35回大会 優秀発表賞 2021.09.25
- 前田 奈穂子, 日本宇宙生物科学会第35回大会 優秀発表賞 2021.09.25
- 尾池 貴洋, ITCCIR2020, 最優秀賞
- 安達 拓也,第58 回群馬放射線腫瘍研究会,優秀発表賞
- 吉田 由香里, ITCCIR2020, コースディレクター賞
- 武者 篤, 第74 回日本口腔科学会学術集会, Web 学会賞
- 武者 篤, 北関東医学会奨励賞
- 武者 篤, 日本放射線腫瘍学会 第33 回学術大会 講演 高評価ベスト10
- 武者 篤, 日本放射線腫瘍学会 第33 回学術大会 優秀発表 ベスト50
- Takahashi A, Elsevier, One of the Most Valued Reviewers from 2019 (Life Science Space Research). 2020
- Sakai M. IOP Publishing Outstanding Reviewer Awards. 2020
- 佐藤浩央. 第78回 日本医学放射線学会総会 優秀論文賞.
- Sato H. ITCCIR 2019. Silver prize. 2019
- Yusa K, Okamoto M. ITCCIR 2019. Bronze prize. 2019
- 久保田佳樹, 岡本雅彦, Yang Li, 他. 日本放射線腫瘍学会第32回学術大会. 優秀教育展示賞. 2019
- 吉田由香里. 日本放射線影響学会奨励賞. 2019
- 馬立秋. 国際癌治療増感研究協会国際研究奨励賞. 2019
- 脇畑庄人, 群馬大学生命医科学専攻, 学長表彰, 2019
- 富永信太朗, 群馬大学生命医科学専攻, 学長表彰, 2018
- Kubota Y, ITCCIR 2017, Gold prize, 2017
- Sakai M, The 8th JKMP, Yong Investigator Award, 2017
- Prajuli RK, Nepal Bidhya Bhusan Award “A” & Gold Medal, 2017
- 瀬下幸彦, 群馬大学生命医科学専攻, 学長表彰, 2017
- Tashiro M, ITCCIR 2016, 敢闘賞, 2016
- Takahashi A, ISRN-2016, Scientific Dream Award, 2016
- 高橋昭久, 日本健康開発財団, 最優秀賞, 2016
- 高橋昭久, 日本宇宙生物科学会第30回大会, 学会賞, 2016
- 吉田由香里, 日本放射線腫瘍学会, 梅垣賞, 2016
- 安藤 興一, 放射線影響学会, 功績賞, 2016
- 酒井真理, 第113回医学物理学会 大会長賞, 2016
- Takahashi A., ICRR 2015, Excellent Poster Award, 2015
- 松村彰彦, ITCCIR 2015, 金賞, 2015
- 松村彰彦, ITCCIR 2015, 銅賞, 2015
- Sakai M, The 7th KJMP, Oral Presentation Award, 2014
- Nagatake K, The 7th KJMP, Poster Presentation Award, 2014
- Tashiro M, Radiological Physics and Technology, Doi Award in Radiation Therapy Physics, 2014
- Tashiro M, ITCCIR 2013, Silver Prize, 2013
- Tashiro M, JKMP05, Poster Award in Radiation Therapy, 2005
Press Release
- 2020/4/8, 原子力産業新聞, 重粒子線がん治療最前線
- 2019/7/24, 新たな高性能画像診断機器である「医療用コンプトンカメラ」を開発し、世界で初めての臨床試験に成功―PET薬剤とSPECT薬剤の同時計測・画像化に成功―(Link)
- 2017/6/9, 朝日新聞, 中小メーカー 医療に参入
- 2017/6/5, 上毛新聞, 最先端癌治療を保険会社員ら見学
- 2017/4/14, 毎日新聞, 「見える化」 世界初の実証成功 量研機構 /群馬
- 2017/4/14, 上毛新聞, がん治療を〝見える化〟 粒子線の副作用軽減狙う 高崎量子研
- 2016/10/2, 上毛新聞, 重粒子線施設で最新癌治療を 群大が見学会
- 2015/7/20, ぐんま経済新聞, 放射線診断装置を共同開発【矢島工業と群馬大】