研究実績

Articles

  1. Takahashi A, Wakihata A, Ma L, Adachi T, Hirose H, Yoshida Y, Ohira Y. "Temporary Loading Prevents Cancer Progression and Immune Organ Atrophy Induced by Hind-Limb Unloading in Mice". Int J Mol Sci. 19, 3959, 2018
  2. Sakai M, Parajuli RK, Kikuchi M, Yamaguchi M, Nagao Y, Kawachi N, Arakawa K, Nakano T. "Effect of number of views on cross-sectional Compton imaging: A fundamental study with backprojection". Phys Med. 56, 1–9, 2018
  3. Yoshida Y, Tominaga S, Ma J, Takahashi A. "Heat induces histone γH2AX gormation under hypoxia". Theram Med, 34(3), 45-51, 2018
  4. Hirano Y, Kodaira S, Souda H, Matsumura A, Torikoshi M. "Linear energy transfer (LET) spectra and survival fraction distribution based on the CR-39 plastic charged-particle detector in a spread-out Bragg peak irradiation by a 12C beam". Phys Med Biol. 63:185006, 2018
  5. Sakai M, Yamaguchi M, Nagao Y, Kawachi N, Kikuchi M, Torikai K, Kamiya T, Takeda S, Watanabe S, Takahashi T, Arakawa K, Nakano T. "In vivo simultaneous imaging with 99mTc and 18F using a Compton camera". Phys Med Biol. 63(20):205006, 2018
  6. Paz A, Yamamoto N, Sakama M, Matsufuji N, Kanai T. "Tumor control probability analysis for single fraction carbon ion radiotherapy of early-stage non-small cell lung cancer". Int J Radiat Oncol Biol Phys. 102(5), 1551–1559, 2018
  7. Lee SH, Sunaguchi N, Hirano Y, Kano Y, Liu C, Torikoshi M, Ohno T, Nakano T, Kanai T. "A carbon CT system: how to obtain accurate stopping power ratio using a Bragg peak reduction technique". Phys Med Biol. 63 035025, 2018
  8. Sakai M, Kubota Y, Saitoh J, Irie D, Shirai K, Okada R, Torikoshi M, Ohno T, Nakano T, "Robustness of patient positioning for inter-fractional error in carbon ion radiotherapy for stage I lung cancer: bone matching versus tumor matching", Radiotherapy and Oncology, 129, 95–100, 2018
  9. Hirano Y, Kodaira S, Souda H, Matsumura A, Torikoshi M, Linear energy transfer (LET) spectra and survival fraction distributionbased on the CR-39 plastic charged-particle detector in a spread-out Bragg peak irradiation by a 12C beam, Phys Med Biol. 2018;63(18):185006
  10. Takahashi A, Yoshida Y, Wakihata S, Ohira Y. "Combination effects of space radiation and zero-gravity". Gekkan Saibou. 50(12), 640-643, 2018
  11. Takahashi A, Ikeda H, Yoshida Y. "Role of high-linear energy transfer radiobiology in space radiation exposure risks". Int J Particle Ther. 5(1), 151-159, 2018
  12. Bridges D, Kawamura H, Kanai T. "Probabilistic dose distribution from interfractional motion in carbon ion radiation therapy for prostate cancer shows rectum sparing with moderate target coverage degradation ". PLoS One. 2018;13(8):e0203289
  13. Keawsamur M, Matsumura A, Souda H, Kano Y, Torikoshi M, Nakano T, Kanai T. "Development of stereotactic radiosurgery using carbon beams (carbon-knife)". Phys Med Biol 2018;63(4):045024.
  14. Kubota Y, Sakai M, Tashiro M, Saitoh J, Abe T, Ohno T, Nakano T. "Technical Note: Predicting dose distribution with replacing stopping power ratio for inter-fractional motion and intra-fractional motion during carbon ion radiotherapy with passive irradiation method for stage I lung cancer". Med Phys 2018;45(7):3453-3441.
  15. Yoshida Y, Sejimo Y, Kurachi M, Ishizaki Y, Nakano T, Takahashi A. "X-ray irradiation induces disruption of the blood brain barrier with localized changes in claudin-5 and activation of microglia in the mouse brain", Neurochem Int, 2018;119:199-206
  16. Nakagawa Y, Kajihara A, Takahashi A, Murata AS, Matsubayashi M, Ito SS, Ota I, Nakagawa T, Hasegawa M, Kirita T, Ohnishi T, Mori E. "BRCA2 protects mammalian cells from heat shock", Int J Hyperthermia, 2018;34(6):795-801
  17. Yamaguchi M, Nagao Y, Ando K, Yamamoto S, Sakai M, Parajuli RK, Arakawa K, Kawachi N. "Imaging of monochromatic beams by measuring secondary electron bremsstrahlung for carbon-ion therapy using a pinhole x-ray camera", Phys Med Biol 2018;63:045016.
  18. Kubota Y, Hayashi H, Abe S, Souda S, Okada R, Ishii T, Tashiro M, Torikoshi M, Kanai T, Ohno T, Nakano T. "Evaluation of the accuracy and clinical practicality of a calculation system for patient positional displacement in carbon ion radiotherapy at five sites", J Appl Clin Med Phys 2018;19:144-153.
  19. Park SJ, Heo K, Choi C, Yang K, Adachi A, Okada H, Yoshida Y, Ohno T, Nakano T, Takahashi A. "Carbon ion irradiation abrogates Lin28B-induced X-ray resistance in melanoma cells", J Radiat Res, 2017;58(6),765-71
  20. S Abe, Y Kubota, K Shibuya, Y Koyama, T Abe, T Ohno, T Nakano, "Fiducial marker matching versus vertebral body mathching: dosimetric impact of patient positioning in carbon ion radiotherapy for primary hepatic cancer", Physica Medica, 33, 114-120, 2017.
  21. Ikeda H, Souda H, Puspitasari A, Held KD, Hidema J, Nikawa T, Yoshida Y, Kanai T, Takahashi A. , "Development and performance evaluation of a three-dimensional clinostat synchronized heavy-ion irradiation system", Life Sci Space Res, 12, 51-60, 2017
  22. Houweling AC, Fukata K, Kubota Y, Shimada H, Rasch CR, Ohno T, Bel A, van der Horst A, "The impact of interfractional anatomical changes on the accumulated dose in carbon ion therapy of pancreatic cancer patients", Radiotherapy and Oncology, 119(2), 319-25, 2016
  23. Kubota Y, Kawamura H, Sakai M, Tsumuraya R, Tashiro M, Yusa K, Kubo N, Sato H, Kawahara M, Katoh H, Kanai T, Ohno T, Nakano T., "Changes in Rectal Dose Due to Alterations in Beam Angles for Setup Uncertainty and Range Uncertainty in Carbon-Ion Radiotherapy for Prostate Cancer", PLoS One, 11(4), e0153894, 2016
  24. Yamaguchi M, Nagao Y, Kawachi N, Satoh T, Fujimaki S, Kamiya T, Torikai K, Shimada H, Sugai H, Sakai M, Arakawa K, Nakano T, "Detection of a gas region in a human body across a therapeutic carbon beam by measuring low-energy photons", I.J.PIXE, 26(01n02), 61-72, 2016
  25. Ikeda H, Souda H, Puspitasari A, Held KD, Hidema J, Nikawa T, Yoshida Y, Kanai T, Takahashi A. , "A new system for three-dimensional clinostat synchronized x-irradiation with a high-speed shutter for space radiation research", Biol Sci Space, 30, 8-16, 2016
  26. Held KD, Kawamura H, Kaminuma T, Paz AES, Yoshida Y, Willers H, Takahashi A, "Effects of charged particles on human tumor cells", Frontiers Oncol, 6, 23, 2016
  27. Takahashi A, "Molecular damage: Hyperthermia alone", Hyperthermic Oncology from Bench to Besides, , 19-32, 2016
  28. Takahashi A, "Inhibition of DNA repair system activity", Hyperthermic Oncology from Bench to Besides, , 91-108, 2016
  29. Takahashi A, Mori E, Nakagawa Y, Kajihara A, Kirita T, Pittman LD, Hasegawa M, Ohnishi T, "Homologous recombination preferentially repairs heat-induced DNA double-strand breaks in mammalian cells", Int J Hyperthermia, 13, 1-7, 2016
  30. Ando K, Fujita H, Hosoi A, Ma L, Wakatsuki M, Seino KI, Kakimi K, Imai T, Shimokawa T, Nakano T., "Intravenous dendritic cell administration enhances suppression of lung metastasis induced by carbon-ion irradiation", JOURNAL OF RADIATION RESEARCH, 27, 1-10, 2016
  31. Ando K, Goodhead DT., "Dependence and independence of survival parameters on linear energy transfer in cells and tissues", JOURNAL OF RADIATION RESEARCH, 57, 596-606, 2016
  32. Kobayashi D, Oike T, Shibata A, Niimi A, Kubota Y, Sakai M, Amornwhichet N, Yoshimoto Y, Hagiwara Y, Kimura Y, Hirota Y, Sato H, Isono M, Yoshida Y, Kohno T, Ohno T, Nakano T., "Mitotic catastrophe is a putative mechanism underlying the weak correlation between sensitivity to carbon ions and cisplatin.", Scientific reports, 7, 40588, 2016
  33. Isono M, Niimi A, Oike T, Hagiwara Y, Sato H, Sekine R, Yoshida Y, Isobe SY, Obuse C, Nishi R, Petricci E, Nakada S, Nakano T, Shibata A., "BRCA1 Directs the Repair Pathway to Homologous Recombination by Promoting 53BP1 Dephosphorylation.", Cell reports, 18, 520-532, 2016
  34. Takayasu Y, Shino M, Nikkuni O, Yoshida Y, Furuya N, Chikamatsu K., "Oxygen-glucose deprivation increases firing of unipolar brush cells and enhances spontaneous EPSCs in Purkinje cells in the vestibulo-cerebellum.", Neuroscience research, 106, 1-11, 2016
  35. Y Kurosawa, Y Kubota, E Takeshita, R Okada, Y Ohashi, H Souda, T Ishii, T Sutou, T Kanai, T Ohno, T Nakano, A Novel Evaluation Method for Displacement between Carbon Beam Axis and Positioning X-ray Axis Using an Imaging Plate, Nihon Hoshasen Gijutsu Gakkai Zasshi, 72(2), 139-148, 2016
  36. N Mogi, M Sakai, R Okada, Itabashi, H Fukushima, Y Kubota, T Sutou, T Nakano, T Ohno, The impact of gadolinium-based contrast agent for carbon ion radiotherapy. Nihon Hoshasen Gijutsu Gakkai Zasshi, 72(12), 1230-1236. 2016.

Award

  1. 富永信太朗, 群馬大学生命医科学専攻, 学長表彰, 2018
  2. Kubota Y, ITCCIR 2017, Gold prize, 2017
  3. Sakai M, The 8th JKMP, Yong Investigator Award, 2017
  4. Prajuli RK, Nepal Bidhya Bhusan Award “A” & Gold Medal, 2017
  5. 瀬下幸彦, 群馬大学生命医科学専攻, 学長表彰, 2017
  6. Takahashi A., ISRN-2016, Scientific Dream Award, 2016
  7. 高橋昭久, 日本健康開発財団, 最優秀賞, 2016
  8. 高橋昭久, 日本宇宙生物科学会第30回大会, 学会賞, 2016
  9. 吉田由香里, 日本放射線腫瘍学会, 梅垣賞, 2016
  10. 安藤 興一, 放射線影響学会, 功績賞, 2016
  11. 酒井真理, 第113回医学物理学会 大会長賞, 2016
  12. Takahashi A., ICRR 2015, Excellent Poster Award, 2015
  13. 松村彰彦, ITCCIR 2015, 金賞, 2015
  14. 松村彰彦, ITCCIR 2015, 銅賞, 2015
  15. Sakai M., The 7th KJMP, Oral Presentation Award, 2014
  16. Nagatake K., The 7th KJMP, Poster Presentation Award, 2014

Press Release

  1. 2017/6/9, 朝日新聞, 中小メーカー 医療に参入
  2. 2017/6/5, 上毛新聞, 最先端癌治療を保険会社員ら見学
  3. 2017/4/14, 毎日新聞, 「見える化」 世界初の実証成功 量研機構 /群馬
  4. 2017/4/14, 上毛新聞, がん治療を〝見える化〟 粒子線の副作用軽減狙う 高崎量子研
  5. 2016/10/2, 上毛新聞, 重粒子線施設で最新癌治療を 群大が見学会
  6. 2015/7/20, ぐんま経済新聞, 放射線診断装置を共同開発【矢島工業と群馬大】
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